Python Job: Research Officer (PostDoc) – Matrix and Metastasis

Garvan’s 2030: Discoveries to Impact Strategy is designed to galvanise Garvan’s researchers, professional staff, partners, donors and community around our vision of Global leadership in discoveries to impact, and to enable us as an Institute to deliver on that vision – such that Garvan becomes an institute where research discoveries are taken through to patient impact (new treatments, tests and prevention approaches), on a global scale.

Homeostasis of the extracellular matrix (ECM) is critical for correct organ and tissue function. It plays a critical role in normal tissue function and pathological disease progression. Both the biochemical and biomechanical properties of the ECM contribute to modulating the behaviour of resident cells and are more than just passive bystanders. In tissue diseases such as cancer, the ECM undergoes significant change. These changes, driven by both tumour and stromal cells, feed into the progression of the disease. As such, changes in the ECM mark significant transition events in disease progression.

Understanding how the changing ECM facilitates tumour progression and metastasis is an important step in the development of new therapeutic approaches for the treatment of cancer. Our research combines in vitro and in vivo models of disease, in particular breast, pancreatic and lung cancer, to focus on how ECM remodelling influences progression, therapy response, and metastatic dissemination in solid tumours.

The Opportunity & Key Responsibilities

We are currently seeking a dedicated Research Officer (PostDoc) who will be responsible for planning and conducting experiments under supervision within the lab and driving forward the discovery of, development and implementation of novel matrix targeting approaches for the treatment of solid tumours.

Reporting to the Laboratory Head – Matrix and Metastasis, A/Prof Thomas Cox, this is a two year full-time, fixed term position with high possibility for merit-based extension.

Snapshot of benefits

• 2-year fixed term, full time position in the first instance with scope for merit-based extension

• Annual base salary of $94,336 AUD plus 14% superannuation as well as salary packaging benefits

• Ample opportunities for on-going training and development

• Stimulating, diverse and highly international research environment

• Active support from A/Prof Cox aimed as developing your independent career

• 18 weeks paid parental leave

• Additional day’s leave as Garvan Day

• Discounted Health Insurance

• Lifestyle discounts with our community partners

About You

Required Skills

• A PhD (or equivalent) in molecular biology, bioengineering or biochemistry

• A working knowledge of Matrix Biology and/or Cancer Biology

• Exceptional laboratory and analytical skills, with meticulous attention to detail and an ability to carry out high quality work routinely

• Experience with and/or willingness to undertake in vivo research, including handling of small rodents

• Experience with in vitro cell culture of mammalian cell lines

• High motivation and level of commitment to achieving scientific goals

• Excellent time management skills and ability to work independently

• Strong planning and organisation skills, including maintaining scientific records

• Experience in data analysis, including statistics

• Experience in presenting data orally

• Willingness to apply for fellowship grants under the mentorship of A/Prof Cox

• High motivation and level of commitment to achieving scientific goals

• Ability to see opportunities, learn, and apply that learning to drive innovation

• Good networking, collaboration, and teamwork skills

• Confidence in communicating with a wide range of stakeholders

• The ability to work with other staff in a cooperative manner

• Strong verbal and written communication skills in English

Desirable Skills

• Experience in 2D and 3D experimental models of cancer

• Experience in conventional imaging techniques

• Experience in writing scientific publications

• Experience in identifying and applying for funding opportunities

• High quality publication record

• Working knowledge of programming/script languages including Python and/or R

How to Apply

To apply for this position, please submit your application through the Garvan Jobs Portal and be sure to include all of the following:

• An up-to-date CV

• A cover letter addressing the selection criteria, stating why you are interested in, and suited to this role

We are reviewing applications as they are received. If you think you’re the right person for this role, we’d love to hear how your capabilities, achievements and experience set you apart.

The Garvan Institute is one of Australia’s largest and most highly regarded Medical Research Institutes delivering scientific and clinical impact on a global basis.

Garvan promotes a diverse workplace and is committed to the principles of equity, diversity, inclusion and belonging.

Job Type: Full-time

Salary: $94,336.00 per year